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Laurindo LF, Simili OAG, Arajo AC, Guiguer EL, Direito R, Valenti VE, de Oliveira V, de Oliveira JS, Yanaguizawa Junior JL, Dias JA (2025) Melatonin from plants: going beyond traditional central nervous system targetinga comprehensive review of its unusual health benefits

371,372 Atranorin directly binds to ASC and subsequently inhibits ASC aggregation and the formation of NLRP3 inflammasome complexes, thereby reducing the release of IL-1 and IL-18

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